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Black asthmatics less responsive to steroids.


Can vitamins during pregnancy affect child’s wheezing?

 
  
February 16, 2005
  
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Just over half — 56 percent — of readers responding say most patients with chronic rhinosinusitis should be treated empirically with an antibiotic effective against resistant streptococcus pneumoniae.

Do you support Sen. Clinton's proposed Family Asthma Act bill?

What percentage of your patients is from minority groups, underserved, poor and disadvantaged populations?

Distance Learning
2004 ACAAI ANNUAL MEETING
Nov. 12-17, Boston
Link

From the 2003 ACAAI ANNUAL MEETING
Nov. 7-12, 2003, New Orleans

• Two Symposia Online
Link

• Plenary Sessions CD-ROM and DVD
Link

• XI International Food Allergy Symposium,
General Sessions & Symposia
Audio CD & Audio Tape
Link

From the 2002 ACAAI ANNUAL MEETING
Nov. 15-20, San Antonio

• Five Symposia Online
Link


E-mail: k.knauer@UHHS.com
 

Calendar

MARCH
AAAAI Annual Meeting
March 18-22, San Antonio, Tex.
Tel: 414-272-6071
E-mail
Link

April
63rd Annual Course in Allergy & Clinical Immunology
University of Minnesota
April 8, Minneapolis
Tel: 612-626-7600
Link


JUNE

World Allergy Congress
June 26 – July 1, Munich, Germany
Link

JUNE

23rd Annual Aspen Allergy Conference
July 27-30, Aspen, Colo.
Contact: Kathleen Goldy
Tel: 303-282-0491
E-mail
Link


ONGOING
World Allergy Organization Society Meetings

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Top Stories
 
Asthma, allergies during pregnancy may up child’s autism risk
Women who have asthma or allergies during pregnancy may have a higher chance of having a child with autism, says a study in the Archives of Pediatrics and Adolescent Medicine. Scientists from Kaiser Permanente in Oakland, Calif., studied 407 children with autism and 2,095 controls without asthma, looking for a link between asthma, allergies and autoimmune disorders in mothers during the four years surrounding pregnancy and the later diagnosis of autism spectrum disorder in their children. Asthma and allergies were significantly more common in the mothers of autistic children. Asthma and allergies in the second trimester of pregnancy increased the risk of having an autistic child more than two-fold.
    
Black asthma patients may be less responsive to steroids
Regardless of asthma status or severity, black patients seem to require higher doses of steroids than Caucasians, according to a study in Chest. Researchers at the National Jewish Medical and Research Center in Denver looked at 395 asthmatic patients and 202 healthy controls, giving them various tests to assess their responsiveness to steroids. Researchers found that the amount of steroid needed to block immune cell production was significantly higher in blacks than in Caucasians, both in the asthmatic and the non-asthmatic groups.    

Taking vitamins during pregnancy may affect child’s wheeze risk
A mother’s high intake of vitamin C during pregnancy may increase her infant’s risk of developing wheezing as a toddler, while low intake of vitamin E was associated with developing wheezing in the second year of life and eczema among babies born to allergic mothers. The study, in the American Journal of Respiratory and Critical Care Medicine, stressed that the findings may be "spurious," and researchers say not to change the eating habits of expectant mothers. High vitamin C intake can be a marker for higher socioeconomic status and a health-conscious lifestyle, which are factors also associated with increased asthma and allergy.
  

A word from President Myron Zitt, M.D.

The impact of asthma on the well-being of our population and of our health care system is significant. A conservative estimate is that 17 million Americans suffer from this illness at a cost of at least $14 billion a year. While time lost from school and work is considerable, asthma accounts for 500,000 hospitalizations, 2 million emergency department visits and, alarmingly, 5,000 deaths every year.

The burden of asthma, however, falls disproportionately on minority groups, particularly blacks and Hispanics, and on underserved, poor and disadvantaged populations. Blacks are three times more likely to be hospitalized and from three to five times more likely to die from asthma than Caucasians. In New York’s Harlem, the prevalence of asthma, which is rising most rapidly in pre-school aged children, is more than twice that of the general population, while the city’s annual rate of hospitalization was recently reported as 62.9 percent per 10,000 among Hispanics, 59.9 percent among blacks and 12.2 percent among whites. A similar disparity is noted with regard to Emergency Department visits and activity limitations. Yet, inner-city children are least likely to be treated with long-term controller medications, which are recommended by national guidelines for the optimal treatment of persistent asthma.

Children living in inner-city areas are exposed to increased concentrations of indoor pollutants, including cockroach, mold and murine allergens, nitrogen dioxide from natural gas stoves, and second-hand cigarette smoke. High concentrations of ozone in their outdoor play environment also may lead to increased asthma prevalence and exacerbations.

Although research ranging from community intervention trials to studies on the genetic and biomolecular basis for asthma is ongoing, greater efforts must be made to better understand disparities in disease prevalence, clinical course and mortality and to improve outcomes. To this end, the ACAAI is cosponsoring a two-day National Workshop on Asthma Health Disparities organized by Kevin B. Weiss, M.D., director of the Midwest Center for Health Services and Policy Research at the Northwestern University Feinberg School of Medicine with the joint support of the Otho S.A. Sprague Memorial Institute in Chicago. At this February conference, College Representatives Jay Portnoy, M.D., Michael Foggs, M.D., and Santiago Martinez, M.D., are joining members of other co-sponsoring organizations, including AAAAI, ACCP, ALA, AAE, AAFA and AANMA to “identify critical and practical next steps to take in reducing asthma health disparities.”

To further address the issue of asthma health disparities, Sen. Hillary Rodham Clinton is considering the proposal of a bill titled the “Family Asthma Clinical and Environmental Health Research Act” (Family Asthma Act), which can be divided in several sections.

A) Authorizes that $80 million be allotted annually, for fiscal years 2006-2010 for the Secretary of Health and Human Services, acting through the Director of the NIH to award grants to qualified entities, including hospitals, health clinics, medical schools and non-profit institutions for the purpose of establishing pilot projects in:
     a) asthma surveillance, including genetic studies, pulmonary function and tests for exposure to allergens
     b) asthma management

B) Authorizes $6 million over the next five years, to expand the activities of the National Asthma Education and Prevention Program of the NIH. Included would be recommendations as to areas of improvement in federal programs related to asthma, particularly those that:
     a) reduce morbidity, mortality and financial costs
     b) reduce the burden associated with the management of chronic asthma
     c) decrease the burden of asthma on disproportionately affected populations

C) Authorizes $8 million annually to expand the activities of the national Centers for Disease Control and Prevention in both asthma surveillance and prevention activities and in the publication of data regarding childhood asthma prevalence and mortality rates.

D) Authorizes $10 million annually for the next 5 years for funding of fellowships “to train providers to act as asthma specialists in order to increase the number of individuals who can provide comprehensive asthma management to patients.”

Our Board of Regents will be convening in Washington, D.C., in May and hopes to arrange a meeting with Sen. Clinton’s representatives, in an effort to refine the Family Asthma Act. Our motivation is to decrease disparities in asthma care, and improve asthma outcomes. To that end, ensuring that significant funding, as requested in Section D, is provided to train fellows in Allergy and Immunology is essential. We certainly can document that when it comes to asthma care, “nobody does it better than the allergist.”

Myron Zitt, M.D.
President, ACAAI
    
Regulatory Updates
 
GAO: Access to physicians up for Medicare beneficiaries
L recently released study by the Government Accountability Office showed an increase from April 2000 to April 2002 in Medicare beneficiaries’ access to physician care in virtually all parts of the country – both urban and rural areas. The study was requested by Sens. Chuck Grassley and Max Baucus in response to concerns that access to physician services would be compromised as a result of the negative 5.4 percent update for Medicare physician payments in 2002. The study also found that Medicare-participating physicians did not attempt to compensate for the 2002 negative payment update by refusing to accept assignment for Medicare services.
 
Drugs and Devices
FDA issues warning about Zyprexa, Zyrtec errors
The Food and Drug Administration recently issued a warning to physicians and pharmacists about errors in the prescription and dispensation of two medications with similar names: Zyprexa, an antipsychotic manufactured by Eli Lilly, and Zyrtec, an antihistamine manufactured by Pfizer. “From a risk management standpoint, this is an important issue, and points out the importance of writing prescriptions legibly,” ACAAI President Myron J. Zitt, M.D. said.
 
 
Association News
 

Annual meeting symposia online for complimentary viewing
Symposia held at the 2004 ACAAI Annual Meeting in Boston is now online and available for complimentary viewing. The online session features streaming audio/video and includes the speakers’ slide presentation.

Supported by an educational grant from Genentech/Novartis, the Webcast "From Allergen to Asthma: Intervention Points for More than Symptomatic Relief" includes the following presentations:

• Natural History of Asthma and the Possibility of Altering the Course of the Disease – William W. Busse, M.D.

• The Role and Limitations of Systemic and Inhaled Corticosteroids in Asthma Therapy – H. William Kelly, PharmD

• New and Emerging Therapies in the Treatment of Asthma – Alkis Togias, M.D.


Allergy Practice Tip: The Right Encounters
Advice from The Patient-Centered Allergy Practice

Allergists need to see enough patients to provide adequate access but not so many patients that care quality declines. So, what is the right number of patient encounters per day?

According to The Patient-Centered Allergy Practice, the median in allergy practices is 26.5 encounters per day per full-time equivalent (FTE) physician, and 18.65 per FTE provider (all physicians, plus all mid-level providers). This does not include shot patients.

These tips are drawn from The Patient-Centered Allergy Practice, a CME Series in Practice Management, provided by Physicians Practice, endorsed by the American College of Allergy, Asthma & Immunology, and supported through an education grant from sanofi-aventis.

For more advice, visit www.PatientCenteredAllergyPractice.com

 
Fellows-in-Training
 
Welcome to the Board Review Corner prepared by Thao Ngoc Tran, M.D., a representative of ACAAI’s fellows-in-training (FITs) to the Board of Regents. The Board Review Corner is your chance to test your Board preparedness.

To refer to a previous Board Review Corner, click the “Archive” link in the left column.

Immunology Review Corner: Chapter 37 of the 6th edition of Middleton’s Allergy Principles and Practice, edited by N. Franklin Adkinson, et al. Review questions were written by fellows-in-training Drs. Thao Tran, Karla Lowe, Todd Levin and Nathaniel Horne.

Copyright © 2005 American College of Allergy, Asthma & Immunology. All rights reserved.

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