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NAFTA Commission: Asthma increasing among North American children.


Telithromycin linked to
three North Carolina
liver toxicity cases.

 
  
February 1, 2006
  
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More than 86 percent of readers responding value AllergyWatch as an integral part of their CME efforts, and 81 percent voted in favor of a biannual edition of ImmunologyWatch.

Distance Learning
2005 Board/Recertification Review Course:
DVDs, Audio CDs, MP3s
Link

ACAAI Tape Store
Complete Listing
Link

2004 ACAAI ANNUAL MEETING
Nov. 12-17, Boston
Link

From the 2003 ACAAI ANNUAL MEETING
Nov. 7-12, 2003, New Orleans

• Two Symposia Online
Link

• Plenary Sessions CD-ROM and DVD
Link

Patient-Centered Allergy Practice
Endorsed by ACAAI, Sponsored by Physicians Practice
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Calendar

FEBRUARY
ISAAI Lecture Schedule
Illinois Society of Allergy, Asthma & Immunology
Feb. 6
Marriott Chicago Downtown at Medical District
Tel: 847-427-9600
E-mail

MARCH
2006 AAAAI Annual Meeting
March 3-7, Miami Beach
Link

APRIL
AAAAI/ACAAI Certification/Maintenance of Certification Board Review Course
April 6-9
Westin Michigan Avenue Hotel
Chicago, IL
Link

ISAAI Lecture Schedule
Illinois Society of Allergy, Asthma & Immunology
April 23
Marriott Chicago Downtown at Medical District
Tel: 847-427-9600
E-mail

ONGOING
World Allergy Organization Society Meetings

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Top Stories
 
NAFTA Commission: Childhood asthma up in North America
The number of childhood asthma cases is increasing across North America, according to a NAFTA Commission’s first report on children's health and environment indicators on the continent. The report, recently issued by the Commission for Environmental Cooperation (CEC), in partnership with public health organizations and the governments of Canada, Mexico and the United States, also showed improvements in children’s blood levels of toxic substances and fewer deaths from waterborne diseases. The report details 13 indicators of health, under three main categories: asthma and respiratory disease, effects of exposure to lead and other toxic substances, and waterborne diseases. 

Telithromycin linked to three liver toxicity cases
Physicians in Charlotte, N.C., have reported three cases of severe liver toxicity that may have been caused by the ketolide antibiotic telithromycin (brand name Ketek), according to an online issue of the Annals of Internal Medicine. The three cases led to one death and one transplant. All three patients developed acute hepatitis within days of receiving telithromycin, according to the report. In addition, all three had jaundice and abnormal liver function test results. Their viral serologic tests were negative.

Study: HRT, lower BMI increases women’s asthma risk
Hormone replacement therapy (HRT) was linked to a higher asthma and wheezing risk, especially in women with a lower body mass index (BMI), according to a study in Thorax. Scientists analyzed surveys from 2,206 women 46 to 54 years old in Northern Europe between 1999 and 2001, excluding pregnant women and those using oral contraceptives. HRT use increased asthma risk by 57 percent, wheeze risk by 60 percent and hay fever risk by 48 percent. In women with lower BMI, however, the association between asthma and wheeze risk and HRT were significantly stronger.  

IMAP leaders to academic hospitals: Eliminate conflicts of interest
A group of medical leaders from the Institute on Medicine as a Profession (IMAP) is calling for teaching hospitals to be leaders in eliminating conflicts of interest that continue to “characterize the relationship between physicians and the health care industry,” says a report in the Journal of the American Medical Association.
The
group believes more stringent regulation is needed. It has generated several recommendations for institutions to follow, including a complete ban on gift-giving from drug and device makers to physicians and no direct provision of drug samples to physicians.   

  

A word from Dr. Bryan L. Martin, member of ACAAI Board of Regents
At a joint meeting of the Nonprescription Drugs Advisory Committee (NDAC) and the Pulmonary-Allergy Drugs Advisory Committee (PADAC) convened by the U.S. Food and Drug Administration (FDA), held in Bethesda, Md., on Jan. 24, the committees voted 11-7 to recommend that the FDA no longer support the essential use designation of chlorofluorocarbons (CFCs) for use in over-the-counter (OTC) epinephrine MDIs. While this is only a recommendation to the FDA and does not mean that OTC epinephrine MDIs are either banned or doomed, it may begin the process that leads to the withdrawal of allocation of CFC for the manufacturing of these devices — and may ultimately lead to their disappearance from the marketplace.

A decision that may lead to the disappearance of a drug for the market is not easy, and there was a great deal of open discussion regarding the advantages and disadvantages of such a move during the joint meeting. Members of the FDA presented the environmental reasons for the elimination of CFCs and the legal decisions that bind users of CFCs under current guidelines. Industry representatives presented data regarding the use, effectiveness and uniqueness of their medications. Members of the public then had an opportunity to voice their opinions. The committee deliberated, discussed their options and opinions, then voted. It was a very open process, and much of the discussion was pertinent to the practicing allergist.

Allergists were represented at this meeting with a joint presentation from the ACAAI and the AAAAI.

The deliberations of the committee were to the point. Concerns were raised regarding the paucity of data on this drug; although it was pointed out that there were many “older” drugs with limited data on efficacy and safety. There was discussion about the wisdom of having any OTC drug to treat asthma, with recognition of the counter concern
that asthma treatment was expensive and elimination of an OTC bronchodilator may, in some cases, mean patients who could not afford a physician’s visit would go without medications. Some commented that in this day and age, no treatment options for asthma should be OTC. Committee members stated that that the standards that were applied to allow epinephrine MDI to be marketed OTC in the United States about 50 years ago do not apply now. This discussion led to the final 11-7 vote to recommend that the FDA not support continued exemption for use of CFC for epinephrine MDI.  more...

    
Plan to attend the ACAAI-HSACI meeting in Greece
The ACAAI and Hellenic Society of Allergy & Clinical Immunology (HSACI) are co-sponsoring a Joint Allergy Symposium, Allergy Update in Greece, Sept. 6-9, 2006, in beautiful Athens.

This international meeting brings together many of the finest researchers and clinicians to present cutting-edge lectures on the most important topics for the clinical practice of allergy and immunology.

Plan to join your colleagues in Athens, one of the most exciting cities in the world, the metropolis of wisdom, philosophy and inspiration. The modern Athens Ledra Marriott Hotel is the perfect venue for this meeting, with its spacious conference center and view of the Acropolis. 
    
Association News
 

Update your ACAAI Member Profile for the Membership Directory
Look for your Member Profile, which was mailed to all ACAAI members to update information in the Membership Directory. Please be sure to include your current Web site address for the online Allergist Locator . Forms should be returned by Feb. 20, 2006.

Members in the spotlight
ACAAI fellow Dr. Steve Kagen is running for Wisconsin’s 8th Congressional District seat. His campaign Web site is http://www.kagen4congress.com.

Have you written a new book? Have you won a prestigious award? Are you doing something that ACAAI members would find interesting? Submit notable achievements, and read about those of your peers, in ACAAI eNews. Please
e-mail member news notices to joannfaber@acaai.org.

 
Fellows-in-Training
 

Immunology Review Corner
Welcome to the Board Review Corner, prepared by Dr. Karla R. Davis, senior representative of ACAAI’s fellows-in-training (FITs) to the Board of Regents. The Board Review Corner is your chance to test your Board preparedness.

To refer to a previous Board Review Corner, click the “Archive” link in the left column.

Immunology Review Corner: Chapter 62 of the 6th edition of Middleton’s Allergy Principles and Practice, edited by N. Franklin Adkinson, et al. Review questions were written by Drs. Eric Chenworth, Mayo Clinic; Karla R. Davis, Walter Reed Medical Center; Anne K. Ellis, McMaster University; and Soo Kim-Delio, Walter Reed Army Medical Center. 


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