Immunology Review Corner

IImmunology Review Corner: Chapter 70 of the 6th edition of Middleton’s Allergy Principles and Practice, edited by N. Franklin Adkinson, et al.

Prepared by Dr. Karla R. Davis, Walter Reed Medical Center

Chapter 70: Asthma Guidelines and Outcomes

1. Diurnal variation of expiratory flows has been suggested for the diagnosis of asthma, as well as for asthma control and severity assessment. Diurnal variability greater than which of the following is suggested to be significant?

A. 12 percent
B. 15 percent
C. 20 percent
D. 25 percent

2. According to the 1998 revised Global Initiative for Asthma (GINA) Guidelines, peak expiratory flow (PEF) variability of 20-30 percent would fall into which category of asthma severity?

A. mild intermittent
B. mild persistent
C. moderate persistent
D. severe persistent

3. What is the single most effective method to reduce exposure to house dust mite allergen?

A. maintaining relative humidity below 50 percent
B. removal of carpeting
C. use of a high-efficiency particulate air (HEPA) filter
D. encasing mattresses in mite allergen-impermeable covers

4. According to the 1998 revised Global Initiative for Asthma (GINA) Guidelines, peak expiratory flow (PEF) variability of less than 30 percent would fall into which category of asthma severity?

A. mild intermittent
B. mild persistent
C. moderate persistent
D. severe persistent

5. According to the 1998 revised Global Initiative for Asthma (GINA) Guidelines, peak expiratory flow (PEF) between 60 and 80 percent of predicted would fall into which category of asthma severity?

A. mild intermittent
B. mild persistent
C. moderate persistent
D. severe persistent

6. According to the 1998 revised Global Initiative for Asthma (GINA) Guidelines, night-time asthma symptoms more than two times per month would fall into which category of asthma severity?

A. mild intermittent
B. mild persistent
C. moderate persistent
D. severe persistent

7. According to the 1995 Global Initiative for Asthma (GINA) Guidelines, asthma treatment should be reviewed regularly. A gradual stepwise reduction in treatment may be possible if control is sustained for which of the following time periods?

A. at least 1 month
B. at least 2 months
C. at least 3 months
D. at least 6 months

8. Practical recommendations on environmental control measures for house dust mite allergic patients include maintaining relative humidity in the home below which of the following?

A. 90 percent
B. 70 percent
C. 50 percent
D. 30 percent

9. Asthma guidelines suggest which of the following as a target of therapy, rather than for use in guiding treatment?

A. peak expiratory flow (PEF)
B. forced expiratory volume in 1 second (FEV1)
C. symptoms
D. airway inflammation

10. According to the 1995 Global Initiative for Asthma (GINA) Guidelines, addition of a long-acting bronchodilator is first recommended for asthma treatment at which of the following categories of asthma severity?

A. mild intermittent
B. mild persistent
C. moderate persistent
D. severe persistent

Answers:
1. C, Page 1286
2. B, Page 1287
3. D, Page 1288
4. C, Page 1287
5. C, Page 1287
6. B, Page 1287
7. C, Page 1289
8. C, Page 1288
9. D, Page 1287
10. B, Page 1289