Immunology Review Corner

IImmunology Review Corner: Chapter 71 of the 6th edition of Middleton’s Allergy Principles and Practice, edited by N. Franklin Adkinson, et al.

Prepared by Dr. Karla R. Davis, Walter Reed Medical Center

Chapter 71: Asthma and Allergic Diseases During Pregnancy

1. Which of the following increases during pregnancy?
A. Expiratory reserve volume
B. Functional residual capacity
C. Residual volume
D. Tidal volume

2. Which of the following is preserved during pregnancy?
A. Expiratory reserve volume
B. Functional residual capacity
C. Residual volume
D. Total lung capacity

3. Numbers of which of the following cells are reduced during pregnancy?
A. CD4 lymphocytes
B. CD8 lymphocytes
C. Natural killer cells
D. Polymorphonuclear neutrophil leukocytes

4. Use of which of the following asthma medications during pregnancy has been associated with severe unusual cardiac congenital malformations?
A. Albuterol
B. Ipratropium
C. Salmeterol
D. Theophylline

5. Use of which of the following antihistamines during pregnancy has been associated with an increase in oral cleft congenital malformations in a case-control study?
A. Cetirizine
B. Dexchlorpheniramine
C. Diphenhydramine
D. Loratadine

6. Which class of antibiotics should be used to treat bacterial complications of asthma or allergic diseases during pregnancy or lactation?
A. Penicillins
B. Quinolones
C. Sulfonamides
D. Tetracyclines

7. Which vaccine could theoretically potentiate AO hemolytic disease of the newborn infant when given during an AO incompatible pregnancy?
A. Influenza
B. Hepatitis B
C. Pneumococcal
D. Yellow fever

8. If a high-dose inhaled corticosteroid is needed during pregnancy, which of the following medications is recommended?
A. Beclomethasone
B. Budesonide
C. Fluticasone
D. Flunisolide

9. Avoidance of which of the following leukotriene modifiers is recommended during pregnancy?
A. Montelukast
B. Pranlukast
C. Zafirlukast
D. Zileuton

10. In the management of a pregnant woman with acute asthma, an arterial blood gas should be obtained for a pulse oximetry measurement of less than which of the following?
A. 99 percent
B. 95 percent
C. 90 percent
D. 88 percent

Answers:
1. D, page 1303
2. D, page 1303
3. C, pages 1305-1306
4. D, page 1309
5. C, page 1308
6. A, page 1311
7. C, page 1311
8. B, page 1313
9. D, page 1313
10. B, page 1314