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FDA restricts
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Feb. 14, 2007
  
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The top three types of teaching done by readers responding were: patient education, staff education and CMEs.

 

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Periodicals
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Calendar

FEBRUARY
2007 AAAAI Annual Meeting
Feb. 23-27, San Diego
Tel: 888-869-0189 (US/Canada)
Tel: 415-979-2277 (International/Local)
Link


MARCH

IX International Symposium on Respiratory Viral Infections
The Macrae Group
March 3 - 6, Causeway Bay, Hong Kong
Tel: (+1) 212.988.7732
E-mail
Link

APRIL
2007 World Immune Regulation Meeting
April 11-15, 2007
Davos, Switzerland
Email
Link

International Conference on Asthma Impacts of Air Pollution

South Cost Air Quality Management District
April 26-27, Anaheim, CA
Tel: 909-396-2432
Link

JUNE
2007 Annual Meeting of the Florida Allergy, Asthma & Immunology Society
June 8-10, Sarasota, Fla.
Tel: 904-765-7702

2nd World Congress on Work-Related and Environmental Allergy / 6th International Symposium on Irritant Contact Dermatitis
June 13-16, Weimar, Germany
Tel: 49-0-3641-35-330
Email
Link 

JULY

2007 International Congress on Respiratory Viruses
The Macrae Group
July 20-22, Colorado Springs, Colo.
Tel: 212-988-7732
E-mail 
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25th Annual Aspen Allergy Conference
July 24-28, Aspen, CO
Conference Coordinator: Jill Hibbeln
Tel: 720-384-5917
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ONGOING
World Allergy Organization Society Meetings

ACAAI CME Website
Contact: Mary Campbell
Tel: 847-427-1200
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Top Stories
 
Study: Pediatric Exclusivity Program good for kids, economic returns
The U.S. Food and Drug Administration’s Pediatric Exclusivity Program not only improves drug outcomes in children, but also yields economic returns, according to a study in JAMA. Scientists at Duke University Medical College in Durham, N.C., used a cohort study of programs to evaluate the results of pediatric exclusivity trials for nine drugs that were selected using an algorithm from 59 drugs. They also used final study reports submitted to the FDA from 2002 to 2004 to estimate study costs, after-tax outflows and market sales to calculate a net return-to-cost ratio. Findings included: one third of drugs tested had different effects in children than adults. Out of 59 drugs, 12 were ineffective in children and five required dosing changes, and net return-to-cost ratio ranged widely from -0.68 to 73.63.

FDA restricts antibiotic use to pneumonia
The Food and Drug Administration recently restricted Ketek to treating pneumonia and not less serious illnesses. The antibiotic had been linked to rare reports of severe liver problems, including deaths. Ketek will remain on the market with a new warning label. The FDA also reported jointly creating with manufacturer sanofi-aventis a guide for patients, which details Ketek’s risks and safe use.

Prevalence of penicillin sensitization in children declines
There’s been a marked decline in the prevalence of penicillin sensitization among children over a 10-year period, however, most of these reactions are exanthematous and only a fraction is due to IgE-mediated penicillin allergy, according to a study in the Annals of Allergy, Asthma, and Immunology. Researchers at Washington University School of Medicine, St. Louisexamined penicillin skin test reactivity trends over time, assessing the relative distribution of specific reagents related to a positive skin test result. They also looked at whether reaction history was predictive of the presence or absence of a positive skin test result. From 1993 to 2003, penicillin testing was administered using three reagents: benzylpenicilloyl polylysine, penicillin G, and sodium penicilloate. Of the 359 prospectively evaluated children, 23 had a positive skin test reaction. Twenty-two of these occurred in 1993 and one in 2002. 
 
A message from
Editor-in-Chief Dr. Gailen D. Marshall,
Annals of Allergy, Asthma & Immunology

I am pleased to update the membership on the state of the Annals at the invitation of President Dan Ein. The first year with our new team has been completed, and we have had many successes and are addressing existing and new challenges. I am pleased to report that we are making steady progress in improving the quality and quantity of articles for our readers in each monthly issue. This is based on improving the requirements for conciseness of each article and a more rapid, efficient review system. We have developed an operational strategy with the goal of publishing articles within three months of final acceptance and providing a first decision within three weeks of initial submission. Thus, for authors who submit manuscripts that require little or no revision and are sensitive to timelines for resubmissions, galleys, etc., it will soon be possible for authors to see their work in print in as little as four months after initial submission.

There are many people who make the process work optimally — beginning with the Annals office staff, led by Kim Stamper, our managing editor, and featuring Treasa Rowzee, our editorial assistant. They are the initial contacts for authors with questions or concerns about the process. The College office in Arlington Heights, Ill., has been outstanding with its help and support in the publication of the Annals. Led by the efforts of Mary Lou Callaghan, the College serves as our publisher, negotiating contracts with our peer review system providers (editorial manager), copy editors and printer (Cadmus), as well as providing support for the College editorial office in Jackson, Miss. Without that support from headquarters, we could not bring you a publication which, in my heart of hearts, I sincerely believe will one day be widely regarded as the No. 1 allergy-immunology journal in the world for the practicing clinician.

The Associate Editorial team is second-to-none in the world in dedication and expertise. Drs. Sami Bahna, Leonard Bielory, Walter Canonica, John Moffitt, Steve Tilles, and Dick Weber have each done a great job in handling the more than 500 manuscripts that were submitted in 2006 and selecting the best of the best for publication in each issue of the Annals. I am pleased to announce that 2007 has brought us two new associate editors – Drs. Mike Tankersley and Mitch Grayson. They have already begun their work and add even more expertise to an already talent-laden group. This will allow us to process even more manuscripts in a more rapid and efficient fashion. Authors, are you listening?

The peer review process depends on the willing participation of volunteer reviewers. We have some wonderful reviewers, the most active of which serve on our editorial board. The peer review process is central to the process of publishing objective, useful, relevant, well-written manuscripts. There is value in reviewers of diverse background who share the common goal of critiquing manuscripts for content, writing clarity, and conciseness. Those of our readers who wish to be reviewers for the Annals can sign up at our new Web site. If you think you are signed up but have not been asked to review, please log in and check that you have listed areas of expertise/interest in your profile. Almost all of our reviewers are now selected based on their self-described areas of interest/expertise. If you have not logged onto our new site since October and have not been asked to review, it is likely that you are not in the database as a reviewer. If you are listed but still have not been invited, please send me an e-mail (gmarshall@medicine.umsmed.edu) so I can investigate. We want as many of you as possible who want to review to have the opportunity to do so.

Finally, a few words about future challenges facing the Annals. The degree of advertising in all medical journals has steadily diminished over the last few years, and there is no real end in sight. Direct-to-consumer advertising is where the money appears to be going. That means we must find other revenue streams to maintain/improve the financial base for our journal. (We are already working on it, but are open to new ideas). Another area of challenge is the increasing (and largely appropriate) demand for transparency — disclosure of conflicts of interest for authors, editors, and reviewers, clinical trial registration, the problem of ghost-written manuscripts, and the disturbing worldwide trend of disparities between positive results published by industry-sponsored and non industry-sponsored studies. Rest assured that your Annals leadership team is working constantly to address these and other issues that will preserve the honorable reputation of our journal. We want to continue and steadily improve the reputation that articles published in the Annals are of the highest quality, caliber, and integrity.

Your Annals staff is hard at work. Stay tuned – the best is yet to come.
 
Association News
 
SPECIAL BULLETIN: Immunotherapy may not be adequately presented in the new NHLBI asthma guidelines.
As you may have heard, the new guidelines for the management of asthma have been made public in DRAFT version, by the NHLBI.

“The Executive Committee of the College is concerned that immunotherapy is not adequately presented as a bona fide treatment for asthma,” said ACAAI President Dr. Daniel Ein. “There is a section on immunotherapy to be found on page 148 of the document and some other mentions of it elsewhere.

“If, however, one looks at the proposed treatment steps in the tables for management of asthma, there is no mention of immunotherapy. (Look at Figure 4-6 on page 517 in Component 2 of the document). This is particularly troublesome because most of the readers of the guidelines will only look at the tables and this is where immunotherapy needs to be included,” Dr. Ein said.

The draft of the Full Report of Expert Panel: Guidelines for the Diagnosis and Management of Asthma (EPR-3) has been posted on the NHLBI Web site for public review and comment through March 5. The URL is: http://www.nhlbi.nih.gov/guidelines/asthma/epr3

We urge you to send your comments to NHLBI to point out this shortcoming in the document. All comments must be submitted electronically using the “review and comment form” on the NHLBI Web site.
 

Save the date for the College meeting in Dallas, Nov. 9-14
The 2007 ACAAI Annual Meeting in Dallas, Nov. 9-14, will be held at the Gaylord Texan Convention Center. Standing tall on a peninsula jutting out onto Lake Grapevine, the Gaylord Texan is a tribute to everything Texas. Its atriums – housing 4.5 acres of gardens under glass – are filled with the spirit of the open plains, legendary vineyards, and the winding Rio Grande.

The Gaylord Texan includes the finest in regional cuisine at a choice of restaurants, offering live music, entertainment, dining, and dancing at the Glass Cactus overlooking the lake. Shoppers can visit the unique stores and markets on site, or take the free shuttle to downtown Grapevine or Grapevine Mills, the largest shopping mall in Texas.

For recreation and relaxation, there is something for everyone, including:
Biking, jogging trails, and horseback riding
World class spa and fitness center, a contemporary outdoor pool, and a 20-meter indoor lap pool
18-hole golf course at nearby Cowboys Gold Club
Boating, waterskiing, jet skiing, and fishing on Lake Grapevine.

Join your colleagues in this wonderful setting brimming with authentic Texas style and hospitality. Look for more information about the College meeting in ACAAI eNews and ACAAI News.


Gaylord Texan Lone Star Atrium

The College and AANMA expand lobbying activities on Capitol Hill
The College’s May 3, lobbying trip to Washington, D.C.. coincides with the Allergy & Asthma Network Mothers of Asthmatics (AANMA) 10th annual Asthma Awareness Day on Capitol Hill, April 30-May 2.

AANMA activities: Expanded activities this year include a three-day national asthma conference for physicians, medical care providers, patients, and families. Sessions critical to patient care include safe medication, the MDI transition to HFAs, and emergency preparedness. Workshops include teaching advocacy skills, preparing your message, and presenting it to members of Congress and their staffs on the last day of the conference.

Visit AANMA’s Web site or call 800-878-4403 for continuing updated information. You can also refer to the conference flyer included with the most recent issue of ACAAI News. The deadline for registration is March 15.

College activities: The Board of Regents fourth annual trip to Capitol Hill has been expanded to include invited College members to participate at their own expense. Activities include a legislative workshop and meetings with Congressional representatives and staff. For more information on participating in the legislative visits, contact Rick Slawny at rickslawny@acaai.org.

Prescribing data: the choice is yours
As a physician, you deserve to be able to choose who has access to your prescribing data.

The AMA Physician Data Restriction Program (PDRP) makes that decision yours alone by empowering you to determine whether the prescribing data you generate is made available to pharmaceutical companies. It lets you opt out of sharing prescribing data with pharmaceutical representatives, if you want. Yet it still keeps the data available to advance important public health benefits, such as timely and appropriate communication about drug recalls and evidence-based medical research.

The AMA does not collect, sell, or have access to prescribing data, but health information organizations match the AMA's Physician Masterfile to prescribing data from other sources. These organizations then license the combination of prescribing data and the AMA Physician Masterfile to pharmaceutical companies. This enables the AMA to ensure compliance with the PDRP.

Visit http://www.ama-assn.org/go/prescribingdata to learn more about PDRP — and how to exercise your choice.

Nycomed acquires ALTANA Pharma; continues sponsorship of
ACAAI eNews

On Jan. 1, Nycomed announced the official launch of the combined group following the acquisition of ALTANA Pharma. ACAAI eNews has been sponsored by ALTANA Pharma since November 2002, and the College is grateful for Nycomed’s continuing support.

Nycomed will now focus on integrating the two companies, while ensuring that the high level of customer service is maintained. The integration steps include establishing a new corporate headquarters in Zurich, Switzerland, which is expected to be in place by around May this year.

 
Fellows-in-Training
 

Board Review Corner
Welcome to the Board Review Corner prepared by Soo Kim-Delio, M.D., Senior Representative of ACAAI’s fellows-in-training (FITs) to the Board of Regents. The Board Review Corner is your chance to test your Board preparedness.

To refer to a previous Board Review Corner, click the “FIT Archive” link in the left column.

Review Questions: Chapter 88 of the 6th edition of Middleton’s Allergy Principles and Practice, edited by N. Franklin Adkinson, et al. Review questions were written by Drs. Bret Haymore, Walter Reed Army Medical Center, and Soo Kim-Delio, Walter Reed Army Medical Center.


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