Allergy and Immunology
Review Corner

Chapter 88 of the 6th edition of Middleton’s Allergy Principles and Practice, edited by N. Franklin Adkinson, et al.

Questions prepared by Drs. Bret Haymore, Walter Reed Army Medical Center and Soo Kim-Delio, Walter Reed Army Medical Center.

Chapter 88: Allergic Eye Diseases

1. The eye disease that is considered iatrogenic
A. Perennial allergic rhinitis
B. Bacterial conjunctivitis
C. Giant papillary conjunctivitis
D. Vernal conjunctivitis

2. The two allergic eye diseases considered sight-threatening:
A. Bacterial conjunctivitis and perennial allergic rhinitis
B. Bacterial conjunctivitis and giant papillary conjunctivitis
C. Atopic keratoconjunctivitis and giant papillary conjunctivitis
D. Atopic keratoconjunctivitis and vernal keratoconjunctivitis

3. Which of the following is associated with vernal conjunctivitis:
A. Peak incidence in third decade of life
B. Asian countries
C. Atopy
D. Most common in females

4. Two medications that have both antihistamine and mast cell-stabilizing properties:
A. Olopatadine and levocabastine
B. Ketotifen and azelastine
C. Olopatadine and emedastine
D. Lodoxamide and pemirolast

5. The mast cell stabilizer that appears to be the most efficacious in vernal keratoconjunctivitis:
A. Nedocromil
B. Cromolyn
C. Ketotifen
D. Pemirolast

6. In differentiating scleritis from episcleritis:
A. In episcleritis all redness will blanch shortly after administration of 10 percent phenylephrine
B. Deep boring pain is characterisitic of episcleritis
C. Scleritis is non-sight-threatening
D. Episcleritis is associated with systemic conditions in 40 percent of patients

7. Tears from allergic donors contain significantly less of which anti-inflammatory cytokine?
A. IL-4
B. IL-5
C. IL-6
D. IL-10

8.Which of the following is a sight threatening inflammatory process that generally starts before 10 years of age and resolves with puberty, in patients with atopic backgrounds?
A. Giant papillary conjunctivitis
B. Vernal keratoconjunctivitis
C. Atopic keratoconjunctivitis
D. Seasonal allergic conjunctivitis

9. Which of the following allergic eye diseases is most often associated with wearing contact lenses?
A. Giant papillary conjunctivitis
B. Vernal keratoconjunctivitis
C. Atopic keratoconjunctivitis
D. Seasonal allergic conjunctivitis

10.What is the treatment of choice for mild to moderate allergic conjunctivitis?
A. Oral antihistamines
B. Dual-acting topical with both anti-histamine and mast cell stabilizer
C. Topical NSAID
D. Topical corticosteroid

Answers:
1. C, page 1606
2. D, page 1602
3. C, page 1605
4. B, page 1609
5. A, page 1610 (see also Chapter 53)
6. A, page 1614
7. D, page 1604
8. B, page 1605
9. A, page 1606
10. B, page 1610