|
Allergy and
Immunology
Review Corner
Chapter 5 of Pediatric Allergy: Principles & Practices, edited by Donald Y.M. Leung, et al.
Chapter 5: Inflammatory Effector Cells/Cell Migration
Prepared by Drs. Bret Haymore and Soo Hee Kim-Delio at Walter Reed Army Medical Center.
1. The late-phase asthmatic response is best characterized by:
A. Release of histamine
B. Release of prostaglandin D2
C. Release of cysteinyl-peptide leukotrienes (LTC4, LTD4, LTE4)
D. Increased levels of eosinophils
2. The cytotoxic contents of eosinophil granules are primarily:
A. Eosinophil cationic protein, eosinophil neurotoxin, lymphotoxin
B. Eosinophil cationic protein, superoxide dismutase, eosinophil peroxidase
C. Eosinophil cationic protein, eosinophil peroxidase, eosinophil neurotoxin
D. Eosinophil cationic protein, eosinophil peroxidase, lymphotoxin
3. Which of the following is the most important stimulus for mast cell development in the bone marrow:
A. IL-5
B. IL-13
C. IL-17
D. Stem cell factor
4. The stem cell factor receptor on mast cells is called:
A. Transforming growth factor receptor
B. C-kit
C. Fc epsilon RI
D. CCR3
5. Which of the following cells completes its maturation outside of the bone marrow?
A. B cells
B. Basophils
C. Eosinophils
D. Mast cells
6. Which cytokine is most associated with pulmonary alveolar proteinosis:
A. Stem cell factor
B. GM-CSF
C. Lymphotoxin
D. RANTES
7. Which of the following is involved in the presentation of glycolipids to T cells?
A. CD1
B. CD4
C. CD8
D. CD80
8. Dendritic cells produce which chemokine receptor that binds MIP-3alpha and beta-defensin?
A. CCR3
B. CCR6
C. CCR7
D. CCR9
9. Which chemokine receptor appears to be the predominant eosinophil chemokine receptor?
A. CCR3
B. CCR6
C. CCR7
D. CCR9
10. Which of the following statements are true about CCR1 and CCR2?
A. They are induced on monocytes only after IL-2 stimulation.
B. They are induced on lymphocytes only after IL-2 stimulation.
C. They are constitutively expressed on lymphocytes.
D. They are induced on monocytes only after IL-10 stimulation.
Answers
1. D, page 51
2. C, page 53
3. C, page 54-55
4. B, page 55, box 5-3
5. D, page 54-55
6. B, page 56
7. A, page 57
8. B, page 57
9. A, page 63
10. B, page 61
|
