| |
You are
selecting an unrelated donor for a 40-year-old man with AML in second complete
remission with high-risk cytogenetics. He is CMV seronegative with blood
type A-. He has no siblings. The search coordinators have
identified the following options:
|
Option
|
Age/Six
|
HLA
Matching
|
CMV
Status
|
Blood
Type
|
|
|
|
|
|
|
|
Donor 1
|
50F
|
9/10
allele mismatch at HLA-A
|
CMV-
|
A+
|
|
|
|
|
|
|
|
Donor 2
|
30M
|
9/10
allele mismatch at HLA-C
|
CMV+
|
O+
|
|
|
|
|
|
|
|
Donor 3
|
30M
|
9/10
antigen mismatch at HLA-DQ
|
CMV+
|
A+
|
Which
donor would you select?
|
|
|
|
|
|
|
| (A report on the votes will
be presented next month, along with one expert’s commentary.) |
|
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